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    China Business
     May 26, 2012


Globalization comes calling from China
By Benjamin A Shobert

SINGAPORE - Industry leaders gathered this past week at a series of life sciences meetings understand better than most the challenge China presents to their companies. Hailing from the world's leading multinational pharmaceutical, medical device and diagnostic companies, these businessmen and women wrestle every day with how to navigate the challenges and opportunities inherent in China's modernization.

The opportunity for these companies is obvious. Christopher Milne, the Associate Director at the Tufts Center for the Study of Drug Development in Boston, shared with attendees at this week's NextLevel Pharma event that "it is estimated that 800 million people in China do not have access to care through large

 

hospitals in major cities."

Even though access remains a problem across the country, the pharmaceutical market alone is growing at around 25% a year, from US$41 billion a year in sales in 2010 to a projected total of $125 billion by 2015. Much of this growth is going into generics, no surprise given basic drugs for pain management and blood pressure - as only two examples - have historically not been widely available across the country.

Gavin Outteridge, vice president at Kinapse, who said that Beijing must determine how to "extend basic healthcare to the rural population", best captured the business challenge inherent in accessing China's domestic market. From the point of view of payers - whether they are from government, private insurers or individuals - is to "increase access while controlling costs." At least in the short term, increasing access is going to be a conversation largely dominated by cost. Industry understands the opportunity within China's domestic market is a two-edged sword.

Accessing China's enormous potential means being willing and able to live with lower margins. Managing the trade-off between lower prices spread across larger volumes is part of what has driven provincial governments to adopt aggressive pricing strategies like that Anhui has put forward. In the short-term, the Anhui Model has lowered costs and improved access, but it has set in motion quality problems and created a race to the bottom among China's domestic drug manufacturers.

Professor Liu Peng, an Assistant Professor with the Institute of Healthcare Reform and Development at Renmin University in Beijing, shared this week his concerns that while the Chinese domestic pharmaceutical companies are "large in scale [and] rapidly growing, they have relatively low technology and quality." To Peng, "… that is why Chinese domestic manufacturers are not sustainable."

Like many strategic sectors driven by the central government either as part of a Five-Year Plan or a parallel strategic focus, China's domestic pharmaceutical companies have not yet proven they can be measured based on successful commercial outcomes. Rather, their success to-date has to be gauged by their compliance with Beijing's objectives of increasing access at lower costs.

As Professor Liu points out, this brings to mind whether they are sustainable businesses and, if not, whether China has simply kicked the can down the road relative to how to expand coverage without the full participation of commercially driven multinationals.

Liu drew this out in more detail when he acknowledged that in China their exists "a philosophical debate between whether the country's healthcare reform process should be market-driven or state-driven." He admitted, "It is likely the final policy outcome is going to be mainly state-driven, but the market will have some partial wins." If this proves to be the case, the implications to multinationals are troubling. Certain players in this sector will shrug this off as more of what they already knew and have been dealing with in China for the last 30 years.

Companies like Johnson & Johnson will likely find their brand value, and the trust that Chinese consumers place in their products given the numerous quality problems from domestic manufacturers, may allow them to continue to build market share in over-the-counter (OTC) products.

But for product lines where the consumer has less knowledge or visibility of the brand, or where government has the power to simply mandate which drug manufacturer is selected as part of a nationalized formulary, this brand allegiance will likely be of little help. Consequently, multinationals in these categories may find China an increasingly difficult market.

The traditional strategic response to this sort of market dynamic is to focus on increasingly innovative drugs; however, in a market Outteridge characterized as "struggling to fund the basics", this may not be a successful response. If international players find the Chinese domestic market limited in terms of revenue growth, what other opportunities can they pursue?

Many multinationals in China are exploring not only the potential to sell into the domestic economy, but also to use the country's large pool of scientists as a way to develop new products both for China's own market as well as for potential exports. Many large companies like Pfizer, GSK and Eli-Lilly are already using China as source of low-cost, high technology drug discovery.

Two issues limit how successful these strategies are likely to be: first, China's history of lax enforcement of intellectual property (IP) and second, the perception by industry that innovative research may not yet be something China's research community is ready to produce.

Because China's IP legacy remains a problem, multinational pharmaceuticals in particular have begun teaming up with former Chinese employees of their own companies who have elected to return to China and start their own research businesses. Companies like Roche have seen a surprising number of Chinese employees get trained at American universities, learn the industry working in US companies, and now head back to China.

Working with former employees helps American and European companies feel more comfortable in the risks they are taking, but most go one step further and actually break apart the research they outsource into smaller sub-sections that are on their own of little value, but when consolidated are quite valuable.

The second challenge industry faces as it attempts to develop domestic research competencies within China is the legacy of group-think that runs deeply within China's educational system tied to the country's view of rigid hierarchies, neither of which is helpful when trying to draw innovation out of researchers. Some companies are attempting to deal with this by focusing their Chinese R&D on process innovation, while others believe that this represents a very short-term challenge, and one that the country as a whole is preparing to break out of, not only in the life sciences, but in other portions of the global economy as well.

These two issues raise the question of what to make over the next phase globalization appears to be entering. The traditional argument about globalization was that developed economies like those in the United States and Europe could afford to allow certain industries and certain types of work migrate away from their countries and go towards countries like China.

Most of the lost jobs were in what were commonly referred to as high-labor content, low technology, heavy industry and manufacturing. What would be left for the developed economies would be high technology industries and high touch service businesses, neither of which were segments of the global economy most believed China would be successful within.

What the life sciences segment of the economy in general, and pharmaceuticals in particular, suggests is that this traditional model of what China would be proficient at, and what would remain within the purview of America and the EU, is rapidly changing. China's ability to rapidly move up the value chain has already been seen in clean technology and high-speed rail.

Both industry segments evolved from extremely rudimentary manufacturing competencies, and built up their know-how around process innovations, until today Chinese companies stand as the world's leaders in both areas.

Could this also happen in the life sciences space? Certainly it could, and many already believe the process is well under way. The bigger question is how American and European politics will respond if they discover that portions of their national industry which they believe safe from Chinese competition prove to be equally vulnerable as their manufacturing sector has proven to be.

As China's capabilities in these areas grows, it will become increasingly difficult for either popular culture or conventional politics to avoid the realization that China's entry into the world's economy has forever intensified and accelerated what nations, businesses and individuals must do in order to stay viable.

Whether the developed nations have the vision to respond, or willingness to absorb this lesson and commit themselves to personal and national sacrifices necessary to compete against China remains to be seen. If not, China's nascent efforts to move up the value chain in the life sciences industry may well mark a moment where political recrimination against China becomes the more convenient and palatable choice, and one developed economies find popular support pursuing.

Benjamin A Shobert is the Managing Director of Rubicon Strategy Group, a consulting firm specialized in strategy analysis for companies looking to enter emerging economies. He is the author of the upcoming book Blame China and can be followed at www.CrossTheRubiconBlog.com.

(Copyright 2012 Asia Times Online (Holdings) Ltd. All rights reserved. Please contact us about sales, syndication and republishing.)





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